京津冀国家技术创新中心“淘沙取金”，全链条培育颠覆性技术

Core Insights - The article highlights the groundbreaking technology developed by the Beijing-Tianjin-Hebei National Technology Innovation Center, which includes a miniature multi-photon microscope capable of real-time imaging of freely moving mice's neurons, even in space [1][2]. Group 1: Technology Development - The miniature multi-photon microscope weighs only 2.2 grams and can be worn on a mouse's head, allowing for the observation of neuronal activity in real-time during free movement [2]. - This technology enables imaging of the entire cortex and hippocampus of the brain, providing critical data for neuroscience research and behavioral studies [2]. - The device has been utilized in over 60 top research institutions, yielding more than 20 high-quality research outcomes [2]. Group 2: Innovation Center's Role - The Beijing-Tianjin-Hebei National Technology Innovation Center was established to support China's first comprehensive national technology innovation center, focusing on disruptive innovation and collaborative development in the region [4]. - The center employs around 100 dedicated technical managers to oversee the entire lifecycle of projects, from discovery to implementation [4][5]. - The center has a distributed work structure with a hub in Beijing and branches in major cities globally, allowing for the identification of approximately 5,000 disruptive technology projects annually [4]. Group 3: Project Evaluation and Support - The center evaluates disruptive technologies based on a unique filtering process that considers seven dimensions, ensuring that only projects with strong potential are selected [5]. - Financial support for projects varies, with early-stage projects receiving between 300,000 to 2 million yuan, depending on their development stage [7]. - The center has cultivated around 130 companies, with 40% of them expanding from outside the Beijing-Tianjin-Hebei region, and has a project reserve of over 400 disruptive potential projects [8].