Zhi Tong Cai Jing·2025-08-15 01:37Core Viewpoint - The valuation logic of Fosun Pharma is undergoing a silent reconstruction following a significant licensing deal for its innovative drug XH-S004, which has led to a notable increase in its stock price and market recognition [1][3]. Group 1: Licensing Deal and Market Reaction - Fosun Pharma announced a global licensing agreement for its oral DPP-1 inhibitor XH-S004 with Expedition Therapeutics, with a potential total transaction value of $645 million (approximately 4.6 billion RMB) [1]. - Following the announcement, Fosun Pharma's H-shares surged by 9.4% and A-shares rose by 5.6%, indicating strong market approval of the deal [1]. - XH-S004 is currently in Phase II clinical trials for non-cystic fibrosis bronchiectasis and Phase Ib trials for chronic obstructive pulmonary disease (COPD) in China [1]. Group 2: Strategic Partnerships and Market Position - Expedition Therapeutics focuses on innovative therapies for autoimmune diseases and has a management team with extensive experience in drug development and commercialization [2]. - The collaboration aims to expand the global reach of XH-S004 for treating non-cystic fibrosis bronchiectasis and COPD patients [2]. - The DPP-1 inhibitor market is becoming increasingly competitive, with major pharmaceutical companies like Merck and GSK investing in this area, highlighting the growing demand for treatments for chronic lung diseases [2]. Group 3: Financial and Market Performance - Fosun Pharma's strategic transformation is reflected in its recent issuance of 1 billion RMB in technology innovation bonds, which received a favorable interest rate of 2.70%, showcasing market confidence in its innovative capabilities [3]. - The stock price of its subsidiary, Fosun Pharma's subsidiary Hanhai, has increased by nearly 235% year-to-date, with a total market capitalization of 43.1 billion HKD [3]. - Hanhai's stock performance is closely linked to its innovative product pipeline, particularly in the lung cancer treatment space, with multiple products gaining recognition at major conferences [3][4]. Group 4: Valuation and Investment Strategy - The innovative pipeline, including HLX43, is expected to drive further stock price increases for Hanhai, although it is not yet included in the Hong Kong Stock Connect, limiting direct investment opportunities for some domestic investors [5]. - Investors are advised to consider holding Fosun Pharma to indirectly benefit from Hanhai's innovation while enjoying the stability and risk mitigation from the parent company's diversified business ecosystem [5]. - As of the latest closing on August 14, Fosun Pharma's H-shares were priced at 19.96 HKD, representing a 34% discount compared to its A-share price of 27.97 RMB, indicating a significant valuation gap [5].