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睿智医药:推出STAT6抑制剂评价方案

Core Viewpoint - The company has successfully established an evaluation scheme for in vitro STAT6 inhibitors/degraders, aiding in the development of drugs targeting STAT6 for autoimmune diseases [1] Group 1: Company Developments - The in vitro pharmacological efficacy department of the company has developed a new evaluation scheme [1] - The focus of the evaluation scheme is on STAT6, a key member of the JAK-STAT signaling pathway [1] Group 2: Scientific Background - STAT6 acts as a transcriptional regulatory hub for the IL-4/IL-13 signaling pathway [1] - It plays a crucial role in immune processes such as Th2 cell differentiation and IgE class switching [1] - The protein is significant in regulating immune homeostasis and the pathological processes of autoimmune diseases [1]