贝达药业：MCLA-129双特异性抗体多项适应症临床研究推进中

Core Viewpoint - The company, Betta Pharmaceuticals, provided an update on its dual-target antibody product MCLA-129, which targets both EGFR and c-Met to inhibit tumor growth and survival [1] Group 1: Product Development - MCLA-129 is currently undergoing multiple clinical studies for both monotherapy and combination therapy indications [1] - In January, the I/II phase study of MCLA-129 entered the parallel cohort expansion phase and completed the enrollment of the first subject, targeting wild-type colorectal cancer [1] - In July, a Phase II study of MCLA-129 in lung cancer related to driver gene positivity and MET amplification completed the enrollment of its first patient [1] Group 2: Combination Therapy Trials - Clinical trials for MCLA-129 in combination with Bevacizumab are progressing [1] - The application for clinical trials of MCLA-129 in combination with Ensartinib has recently been accepted by the NMPA [1] Group 3: Communication and Disclosure - The company will timely disclose any significant progress in the aforementioned clinical studies [1]