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药明巨诺-B涨超10% 上半年经营性利润减亏良好 新增披露CD19/20双靶点CAR-T管线

Core Viewpoint - WuXi AppTec's stock surged over 10% following the release of its interim results, indicating positive market sentiment towards the company's financial performance and future prospects [1] Financial Performance - The company reported a revenue of 106 million RMB for the first half of the year, representing a year-on-year increase of 22.5% [1] - Gross profit reached 65.12 million RMB, showing a significant year-on-year increase of 48.86% [1] - Research and development expenses amounted to 92.04 million RMB [1] Operational Insights - CICC noted that the company's operating profit showed a reduction in losses, primarily due to cost control measures and successful licensing collaborations, with expectations for continued loss reduction throughout the year [1] - The company plans to initiate IIT research for JWCAR201 in hematological malignancies and autoimmune diseases in the second half of 2024, currently in the enrollment phase [1] Product Development - The company holds global rights for JWCAR201, which combines dual-targeting, potentially leading to broader efficacy and higher signal thresholds [1] - Encouraging preliminary data has been obtained for hematological malignancies, with plans to present IIT data at the American Society of Hematology annual meeting in December 2025 [1] - Updates on systemic lupus erythematosus (SLE) data for CD19 CAR-T are also anticipated [1]