Group 1 - Indian pharmaceutical companies are preparing to supply active pharmaceutical ingredients (APIs) for the production of generic versions of Novo Nordisk's weight loss drugs, which will lose patent protection in major markets next year [1] - Major Indian suppliers, including Dr Reddy's Laboratories and Macleods Pharmaceuticals, are focusing on producing APIs for semaglutide, the active ingredient in Novo Nordisk's drugs marketed as "Wegovy" and "Ozempic" [1] - The global market for this segment could reach $94 billion by 2035, as patents for Novo Nordisk's blockbuster therapy expire in countries like Brazil, Canada, India, and China starting in 2026 [1] Group 2 - Dr Reddy's Laboratories has invested in a facility with an annual production capacity of 550 kg of peptide drugs, while Granules India Ltd. has established a subsidiary, Ascelis Peptides, to expand production of various drug APIs, including semaglutide [2] - Smaller suppliers, such as Vasu Jindal's company, have begun selling semaglutide to larger generic manufacturers, with expectations of demand rising to 240 kg annually starting next year [2] - Indian API manufacturers face intense price competition from Chinese companies, which control about 80% of the global supply chain for generic drug APIs [2] Group 3 - The complexity of semaglutide as a biological molecule presents challenges for generic production, prompting companies to prepare in advance of patent expirations [3] - HRV Global Life Sciences is incorporating semaglutide into its research pipeline, highlighting the industry's need for stable, high-quality starting materials and scalable purification processes [3] - The proactive approach of API companies is essential for success in the competitive landscape as they prepare for the upcoming market opportunities [3]
诺和诺德(NVO.US)减重药多地专利明年到期 印度原料药厂商抢滩940亿美元市场