BIOKIN PHARMACEUTICAL(SH:688506) Zheng Quan Ri Bao Zhi Sheng·2025-09-30 04:12Core Insights - Sichuan BaiLi TianHeng Pharmaceutical Co., Ltd. (BaiLi TianHeng), a leader in antibody-drug conjugates (ADC), has re-submitted its application for H-share listing on the Hong Kong Stock Exchange, aiming to accelerate its internationalization strategy and invigorate the biotech sector in Hong Kong [1][5] Group 1: Financial and Market Developments - BaiLi TianHeng successfully raised a total of 3.764 billion yuan through a private placement of A-shares, attracting participation from 18 well-known domestic and international institutions [2] - The funds raised will be used to advance the development of domestic innovative drug pipelines and expand the depth and breadth of its product offerings [2] - The company's market capitalization has exceeded 160 billion yuan this year, reflecting strong investor interest in its innovative capabilities and high-potential pipeline [5] Group 2: Product Development and Clinical Trials - BaiLi TianHeng's core product, BL-B01D1/iza-bren, is a first-in-class dual-target ADC currently in Phase III clinical trials for the treatment of nasopharyngeal carcinoma, with interim analysis meeting primary endpoints [2] - The company has established R&D centers in both the U.S. and China, focusing on early development and subsequent clinical research [3] - BaiLi TianHeng has initiated five clinical studies in the U.S. for BL-B01D1/iza-bren, including three registration trials for triple-negative breast cancer, EGFR-mutant non-small cell lung cancer, and urothelial carcinoma [3] Group 3: Strategic Partnerships and Collaborations - BaiLi TianHeng entered into a collaboration agreement with Bristol-Myers Squibb (BMS) for BL-B01D1/iza-bren, with a potential total transaction value of up to 8.4 billion USD, marking the highest single product transaction in the ADC field [3] - The partnership includes an initial payment of 800 million USD, underscoring the product's significant market potential [3] Group 4: Internationalization Strategy - The decision to list in Hong Kong is part of BaiLi TianHeng's internationalization strategy, aimed at expanding its investor base and enhancing its global brand image [5] - Successful listing in Hong Kong would provide the company with international financing channels and increase its influence in global capital markets [5] - The current favorable conditions in the Hong Kong market for innovative drug companies present a historic opportunity for BaiLi TianHeng [5]