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神州细胞回复定增问询函:拟募资6-9亿元补充流动资金,控股股东全额认购

Core Viewpoint - Shenzhou Cell is planning to raise 600-900 million yuan through a private placement of A-shares to supplement working capital and support R&D efforts, with the controlling shareholder, Lhasa Ailike, subscribing to the entire issuance at a price of 36 yuan per share [1][2]. Fundraising Necessity and Sources - The fundraising is aimed at enhancing operational funds, ensuring R&D investments, and reducing operational and financial risks. Despite revenue growth from 2022 to the first half of 2025, the company faces significant funding needs in the biopharmaceutical and vaccine sectors, with cumulative losses reaching 3.863 billion yuan and a debt ratio of 97.03% as of June 30, 2025 [2]. - Lhasa Ailike's subscription will be financed through a combination of self-owned funds (approximately 440 million yuan) and borrowed funds, with Huanneng Guicheng Trust providing up to 600 million yuan at an interest rate of 5.8% to 7% [2]. Compliance and Stock Price Analysis - The issuance has complied with relevant decision-making procedures and disclosure obligations, aligning with legal regulations and company bylaws. Since the pricing date of June 6, 2025, the company's stock price has increased, reflecting industry trends and operational performance [3]. Previous Fundraising Projects - In the previous public offering, 99.52% of the raised funds were allocated to non-capital expenditures, with adjustments made to improve fund utilization efficiency and align with policy directions and company strategies [4]. Operational Performance Analysis - The core product, Anjia, experienced revenue and gross margin fluctuations due to centralized procurement, with sales revenue declining by 37.99% year-on-year in the first half of 2025 [5]. - R&D expenses have decreased recently as several major products have completed Phase III clinical trials, leading to reduced spending on clinical trial costs [6]. Pipeline Progress and Risks - As of June 30, 2025, the company has one recombinant protein drug and four antibody drugs approved for market, with several products in clinical and preclinical stages. However, there are inherent risks in new drug development, and the company cannot guarantee the timing or success of product approvals [7]. Sales Expense Increase - Sales expenses have risen annually due to new product launches and the expansion of the sales team, with promotional costs including professional service fees and patient welfare projects [9]. Asset and Liability Situation - The company's cash and interest income are well-matched, and there are no issues with fund occupation. The overall aging structure of accounts receivable is good, with sufficient provisions for bad debts [11][12]. - Inventory provisions have been adjusted reasonably, with a significant provision of 95.37% for COVID-19 vaccine products in 2023, which has since decreased [13]. Intangible Assets and Debt Risk - The increase in intangible assets is attributed to growth in R&D technology, and the company has established a robust financial risk management system to ensure debt repayment, despite an increase in borrowing [14][15]. Collaboration with Shiyao Group - The collaboration with Shiyao Group has been terminated, with related funds reclassified in accordance with accounting standards, and this has not adversely affected the company's operations [16].