OPKO Health Reports Third Quarter 2025 Business Highlights and Financial Results

Core Insights - OPKO Health, Inc. reported business highlights and financial results for Q3 2025, including a collaboration with Regeneron Pharmaceuticals and the sale of BioReference Health assets [1][5]. Business Highlights - OPKO entered a research collaboration with Regeneron to develop multispecific antibodies, potentially exceeding $1 billion in value if multiple products succeed, with an upfront payment and milestone payments exceeding $200 million for each program [1]. - The sale of BioReference oncology assets to Labcorp for $225 million, including $192.5 million at closing and up to $32.5 million in performance-based earnout, aims to streamline operations and enhance profitability [1]. - Merck advanced the Phase 1 trial of an Epstein-Barr virus vaccine, with enrollment progressing well [1]. - The first patient was dosed in the MDX2004 Phase 1/2a study for advanced cancers, with data to be presented at the SITC annual meeting [1]. - Abstracts for various drug candidates, including MDX-2001 and OPK-88006, were presented at major medical conferences, indicating ongoing development in immunotherapy and metabolic disorder treatments [1]. Financial Results - Total revenues for Q3 2025 were $151.7 million, down from $173.6 million in Q3 2024, while operating income increased to $48.1 million from $14.2 million [5][13]. - Net income for Q3 2025 was $21.6 million, or $0.03 per diluted share, compared to $24.9 million, or $0.03 per diluted share, in the prior year [5][14]. - Revenue from products was $37.7 million, a slight decrease from $39.1 million in Q3 2024, while revenue from services dropped to $95.2 million from $121.3 million [5][13]. - Total costs and expenses decreased to $80.6 million in Q3 2025 from $84.6 million in the prior year, primarily due to lower sales volume and reduced employee-related expenses [5][13]. Cash Position - As of September 30, 2025, cash, cash equivalents, and restricted cash totaled $428.9 million, with $173.3 million received from the Labcorp transaction [5][11]. - Approximately $73.8 million of OPKO's common stock had been repurchased under the buyback program, with $126.2 million remaining authorized for future repurchases [5].