如何降低肥胖引起的癌症风险？中疾控提示

Core Viewpoint - Obesity is linked to over 200 diseases, significantly increasing the risk of cardiovascular diseases, type 2 diabetes, and various cancers, with approximately 4% of cancers globally associated with obesity [1][2]. Group 1: Impact of Obesity on Health - Obesity disrupts hormonal balance, leading to increased risks of breast cancer, endometrial cancer, and colorectal cancer due to abnormal cell proliferation [2][3]. - Chronic inflammation caused by obesity weakens cellular repair mechanisms and creates an environment conducive to tumor growth, closely linked to liver and pancreatic cancers [2]. - Insulin resistance associated with obesity necessitates higher insulin levels, which may indirectly promote the growth of abnormal tumor cells [2]. Group 2: Cancer Types Associated with Obesity - Weight gain significantly increases the risk of 13 types of cancer, including breast, colorectal, liver, and pancreatic cancers. For instance, a 5-unit increase in body mass index raises the risk of colorectal cancer by approximately 24% in men and 9% in women [3]. Group 3: Strategies to Mitigate Cancer Risk from Obesity - Adjusting dietary habits by reducing high-fat and high-sugar foods while increasing the intake of vegetables, fruits, and whole grains can provide protective nutrients [4]. - Engaging in regular physical activity, such as 150 minutes of moderate exercise weekly, can effectively improve metabolism and reduce inflammation levels [4]. - Emphasizing early screening for related cancers during routine check-ups is crucial for proactive health management [4].