人工合成外泌体实现基因级抗老突破，国产技术“类人源外泌素HME”未来可期

Core Insights - The article discusses the rising interest in artificially synthesized exosomes in the biomedical and skincare fields, highlighting their potential as drug delivery systems and therapeutic agents while addressing challenges related to safety, standardization, and large-scale production [1] Group 1: Artificial Exosomes - Artificial exosomes are nanometer-sized lipid bilayer vesicles secreted by cells, carrying bioactive substances like proteins and RNA, playing a crucial role in intercellular communication [1] - The main advantage of artificial exosomes lies in their controllability and safety, allowing scientists to simulate the effective structure of natural exosomes while eliminating unnecessary components and reducing immunogenicity [1] Group 2: Technological Breakthrough - The company Gu Yu announced a significant breakthrough in September 2025 at Xiamen University, introducing a new anti-aging ingredient called "human-like exosome HME" made using proprietary artificial exosome technology [1][2] - This technology utilizes in vitro biomimetic techniques to create human-like artificial exosomes that accurately mimic the phospholipid bilayer structure of natural human exosomes [2] Group 3: Advantages of Gu Yu's Technology - The technology offers four main advantages: high safety by eliminating risk factors from human-derived exosomes, significant efficacy through precise encapsulation of key components, compliance with regulations, and cutting-edge technology that closely simulates human exosomes [2][3] - The core technology has been granted national invention patent authorization, ensuring complete independent intellectual property rights [3] Group 4: Mechanism and Efficacy - The human-like exosome HME simulates the core functions of exosomes, enabling the release of gene-level anti-aging instructions into cells, effectively guiding them back to a youthful state [4] - Experimental data shows that HME enhances cell proliferation by 1.17 to 1.5 times compared to natural human exosomes and promotes type III collagen generation by 5 to 6.7 times [4] - Human efficacy tests indicate a 17.43% reduction in wrinkle count after 14 days of use, increasing to 26.61% after 28 days [4]