博瑞生物递表港交所:估值偏高、业绩走弱、研发掉队、内控问题频发 资本市场是否买单?

Core Viewpoint - 博瑞生物医药 is attempting a second IPO on the Hong Kong Stock Exchange after a failed attempt in April, driven by a need for international expansion and funding amidst declining performance and cash flow issues [1] Financial Performance - Revenue for 博瑞生物医药 from 2022 to 2024 is projected to be 10.17 billion, 11.8 billion, and 12.83 billion respectively, indicating low growth, while net profit has decreased from 2.4 billion to 1.89 billion, showing a situation of increasing revenue but declining profit [2] - In the first three quarters of 2025, revenue dropped by 10.5% year-on-year to 8.74 billion, with net profit plummeting 71.63% to 503.2 million [2] - The gross margin has fallen from 63.01% in 2022 to 51.4% in the first three quarters of 2025, a decline of over 11 percentage points [2] Debt and Cash Flow - The company's debt ratio has risen from 7.6% at the end of 2019 to 52.77% by September 2025, with total liabilities reaching 28.28 billion, including short-term loans of 1.49 billion and non-current liabilities due within a year of 7.25 billion, while cash reserves stand at only 6.06 billion, indicating a significant repayment gap [2] - In response to cash flow issues, the company initiated a medium-term note issuance plan for 3 billion in 2025, primarily for debt repayment and liquidity support, which increases financial costs [2] Interest Burden and Revenue Composition - Interest expenses for the first three quarters of 2024 reached 48 million, a 22.2% increase year-on-year, nearly matching the net profit for the same period [3] - The raw material drug revenue accounted for 84.23% of total product sales, with antiviral product revenue down 67.06% due to centralized procurement policies, and antifungal product revenue also declining [3] R&D Pipeline and Product Development - Most of 博瑞生物医药's pipeline is in early stages, with the BGM1812 injection for weight loss just having submitted an IND application, and the oral version still in preclinical research [3] - The core product BGM0504 injection is in phase III clinical trials, with a market entry application not expected until 2026, while competitors have already launched similar products, narrowing the market window [4] Historical Financing and Governance Issues - Since its IPO in 2019, 博瑞生物医药 has raised over 12 billion through multiple financing rounds, yet continues to face financial pressure, leading to a new 5 billion fundraising plan in 2024 [5] - The company has faced multiple regulatory warnings over the past five years, including issues with the use of raised funds and misleading statements by management [6] Valuation Concerns - As of November 14, 2025, the company's rolling P/E ratio stands at 377, significantly higher than the industry average of about 30, raising questions about market acceptance of the upcoming IPO amidst declining performance and governance issues [7]