Core Viewpoint - Xinda Biopharma has established itself as a leading player in China's biopharmaceutical sector, particularly in the oncology field, and is expected to continue its growth trajectory with new strategic partnerships and product developments [1] Group 1: Strategic Partnership - On October 22, 2025, Xinda Biopharma entered into a global strategic collaboration with Takeda Pharmaceutical to accelerate the global rollout of next-generation IO and ADC therapies, involving three products: IBI363, IBI343, and IBI3001 [1] - The collaboration includes an upfront payment of $1.2 billion (including a $100 million premium for strategic equity investment) and potential milestone payments, with a total deal value reaching up to $11.4 billion [1] Group 2: Product Development and Commercialization - Xinda will co-develop IBI363 with Takeda, sharing development costs at a 40/60 ratio and splitting profits from commercialization in the U.S. market similarly [2] - IBI363 has shown promising data at the 2025 ASCO conference, with a cORR of 36.7%, mPFS of 9.3 months, and a 12-month OS rate of 70.9% for immune-resistant NSCLC, with a global Phase III clinical plan set to launch soon [2] Group 3: ADC Product Rights - Xinda granted Takeda exclusive rights to IBI343 outside of Greater China, which includes potential milestone payments and high-tier percentage sales sharing [3] - IBI343 is currently undergoing Phase III clinical trials for gastric cancer in China and Japan, and has completed global Phase I/II trials for PDAC [3] - Additionally, Xinda has granted Takeda an option for early pipeline IBI3001 outside of Greater China, which could yield option fees, milestone payments, and high-tier sales sharing if exercised [3]
中国银河证券:维持信达生物“推荐”评级 综合管线领域突破第二增长曲线