美股三大股指大幅低开，纳指跌1.42%

Market Overview - The U.S. stock market opened significantly lower, with the Dow Jones down 0.78%, the Nasdaq down 1.42%, and the S&P 500 down 1.07% [1] - Market expectations for a Federal Reserve rate cut in December fell below 50% for the first time, driven by concerns from Fed officials about persistent inflation above target levels [1] Company Specifics - Applied Materials saw a decline of over 7% despite reporting Q4 earnings and Q1 guidance that exceeded expectations; however, export restrictions to China may lead to a revenue decrease of $600 million by 2026 [1] - Cidara Therapeutics experienced a pre-market surge of 105% following the announcement that Merck will acquire the company for $221.5 per share in cash, with the transaction expected to close in Q1 2026 [1] - Google shares fell nearly 3% after the company announced plans to appeal the European Commission's antitrust ruling and rejected the idea of breaking up its business [1]