我科学家牵头系统绘制非人灵长类多器官衰老分子图谱

Core Insights - The study led by the Kunming Institute of Zoology of the Chinese Academy of Sciences has created a comprehensive baseline map of natural aging across 30 major organ systems in macaques, revealing significant asynchronous aging patterns and molecular characteristics [1] Group 1: Aging Patterns - The research indicates that 12 organs, including the thymus, spleen, gastrointestinal tract, kidneys, and ovaries, age more rapidly, while 11 organs, such as the brain, muscles, liver, skin, and adrenal glands, age relatively slowly [1] - This suggests that aging in various tissues and organs is not uniform, with some organs potentially aging first, thereby affecting the overall aging state [1] Group 2: Molecular Characteristics - The study further identifies key molecular features that contribute to the differences in organ aging, providing new entry points for future anti-aging interventions [1] - The findings establish an important baseline and reference for aging research in non-human primates, which may enhance understanding of human aging mechanisms [1]