Core Insights - Viking Therapeutics (VKTX) shares have increased by 34% over the past three months, driven by positive investor sentiment regarding its obesity drug VK2735 [1][11]. Company Developments - Viking completed enrollment in the phase III VANQUISH-1 study, evaluating VK2735 in obese or overweight adults with at least one weight-related co-morbidity, surpassing the target with approximately 4,650 patients enrolled [2]. - The company also achieved rapid enrollment milestones earlier this year in the phase II VENTURE-Oral Dosing study, which evaluated an oral formulation of VK2735 [3]. - Currently, Viking is enrolling patients in the phase III VANQUISH-2 study, targeting nearly 1,100 obese or overweight adults with type II diabetes, with recruitment expected to complete by early 2026 [5]. Market Context - The obesity drug market is expanding, influenced by the success of competitors like Eli Lilly's Zepbound and Novo Nordisk's Wegovy, indicating strong demand for VK2735 [4]. - The U.S. obesity market is projected to reach $100 billion by 2030, with major players optimizing production and developing new GLP-1-based candidates [7]. - Novo Nordisk and Eli Lilly are racing to introduce oral weight-loss pills, with Novo already seeking FDA approval for an oral version of Wegovy [8]. Competitive Landscape - Eli Lilly is investing in various obesity treatments, with several candidates in clinical development, including orforglipron and retatrutide, and plans to file for regulatory approval for orforglipron later this year [9]. Valuation and Performance - Viking Therapeutics shares are trading at a premium, with a price-to-book (P/B) ratio of 5.84 compared to the industry average of 3.60 [13]. - Despite the recent surge, VKTX shares have underperformed the industry year to date [12].
VKTX Stock Rises 34% in Three Months: Here's What You Should Know