英国和美国敲定药品零关税安排，英方将增加新药支出；外交部回应法国总统马克龙将访华

Market Overview - US stock indices fell on Monday, ending a five-day winning streak, influenced by rising US Treasury yields and weak economic data. The Dow Jones dropped 427.09 points (0.90%) to 47289.33, the Nasdaq fell 0.38% to 23275.92, and the S&P 500 decreased 0.53% to 6812.63. The VIX index rose 5.5% to 17.23 [2][20] - The 2-year US Treasury yield increased by 5.0 basis points to 3.540%, while the benchmark 10-year yield rose by 7.7 basis points to 4.095% [2] Technology Sector Performance - Major tech stocks showed mixed results, with Google down 1.5%, Meta and Microsoft down 1.1%, Oracle down 0.5%, while Amazon rose 0.3% and Apple increased by 1.5% [3][20] - Nvidia announced a $2 billion investment in semiconductor design software supplier Synopsys, leading to a 4.9% increase in Synopsys' stock price and a 1.6% rise in Nvidia's stock [3] Retail Sector Insights - With the onset of "Cyber Monday," large retailers became market focal points. Adobe Analytics projected online sales for the day to reach $14.2 billion. Walmart's stock rose nearly 1%, reaching a historical high [3] Cryptocurrency Market - Cryptocurrency-related stocks weakened as Bitcoin prices fell significantly below $85,000. The total cryptocurrency market cap has evaporated by over $1 trillion since reaching approximately $4.3 trillion at its peak [4] Economic Indicators - The ISM reported that the manufacturing index for November fell to 48.2% from 48.7% in October, marking a four-month low. This indicates that US manufacturing has contracted for nine consecutive months due to ongoing tariff pressures [6] Oil and Gold Prices - International oil prices rose, with WTI crude up 1.32% to $59.32 per barrel and Brent crude up 1.27% to $63.17 per barrel, as OPEC+ reaffirmed its production levels for Q1 next year [7] - Gold prices also saw an upward trend, with COMEX gold futures for December delivery rising 0.50% to $4239.30 per ounce [8]