TRT(SH:600085) Zhong Guo Zhi Liang Xin Wen Wang·2025-12-22 05:22Core Insights - The research conducted by Tongrentang and Beijing University of Chinese Medicine on the quality evaluation of Jiawei Xiaoyao Wan has achieved significant results, with the related paper published in the core Chinese journal "Northwest Pharmaceutical Journal" [1] - The study innovatively established a new quality control model of "dual-dimensional fingerprint map - efficacy component quantification," effectively addressing the technical challenges of simultaneous detection of multiple types of components in traditional Chinese medicine formulas, especially those with weak UV absorption [1] Methodology - The research successfully utilized HPLC-PDA-ELSD dual detector technology to achieve the first-ever simultaneous overall detection and quantitative analysis of both UV-strong absorbing components (such as geniposide) and weak UV-absorbing core efficacy components (such as saikosaponin A and D) in Jiawei Xiaoyao Wan, breaking through the previous bottleneck of undetectable core efficacy substances [1] - The quality monitoring was upgraded from a single indicator to a quantitative model covering the entire "efficacy component group," confirming that eight measured components from the monarch (Chaihu), minister (Mudanpi, Zhizi), and assistant (Baishao, Gancao) herbs are directly related to the core efficacy of Jiawei Xiaoyao Wan, marking a scientific new stage in quality control from "component detection" to "efficacy correlation" [1] Application and Results - The method was applied to test 15 batches of Jiawei Xiaoyao Wan from Tongrentang, showing a high similarity in fingerprint maps (>0.997) and good consistency in the content of efficacy components across batches, demonstrating the excellent and stable quality of Tongrentang's Jiawei Xiaoyao Wan from raw materials to finished products [1] Industry Impact - This research exemplifies Tongrentang's "guarding integrity and innovating" approach, injecting modern scientific connotations into a century-old formula through technological innovation [2] - The new method will provide stronger technical guarantees for the safety, effectiveness, and quality stability of products, offering an innovative "Tongrentang solution" for precise quality control of compound preparations in the traditional Chinese medicine industry [2] - Tongrentang will continue to empower tradition with technology, safeguard health with quality, and contribute to the high-quality development of the traditional Chinese medicine industry [2]