泽璟制药ZG006新品或望获86亿授权收入 科创板6年亏17亿负债率62%拟赴港IPO

Core Viewpoint - Zai Jing Pharmaceutical has announced a strategic collaboration and licensing agreement with AbbVie for the global development and commercialization of ZG006, potentially generating up to $1.235 billion in revenue for the company [1][5]. Group 1: Financial Performance - Zai Jing Pharmaceutical reported a record revenue of 593 million yuan for the first three quarters of 2025, continuing a trend of rapid revenue growth since 2021 [1]. - Despite the revenue growth, the company has not achieved profitability since its IPO in 2020, accumulating a total net loss of 1.738 billion yuan by 2025 [8][9]. - The company has seen a decrease in R&D investment from 509 million yuan in 2021 to 388 million yuan in 2024, with a slight increase in 2025 [9]. Group 2: Strategic Developments - The collaboration with AbbVie grants the latter exclusive rights to develop and commercialize ZG006 outside Greater China, while Zai Jing retains rights within the region [4][5]. - ZG006 is a novel trispecific T-cell engager targeting DLL3, currently in late-stage clinical development for small cell lung cancer and other DLL3-expressing malignancies [4]. - The agreement includes an upfront payment of $100 million and potential milestone payments totaling up to $1.235 billion, significantly enhancing the company's financial outlook [5]. Group 3: Market Position and Future Plans - Zai Jing Pharmaceutical is pursuing an IPO on the Hong Kong Stock Exchange to support its internationalization strategy and enhance brand recognition [2][10]. - The company aims to leverage the collaboration with AbbVie to expand ZG006 into multiple indications and improve its global market presence [5]. - The strategic focus includes addressing unmet medical needs in oncology and blood diseases, with a pipeline covering 29 projects [7].

Zelgen-泽璟制药ZG006新品或望获86亿授权收入 科创板6年亏17亿负债率62%拟赴港IPO - Reportify