21专访丨东阳光药首席科学家林凯:不盲目跟风 做更具创新性的事
2 1 Shi Ji Jing Ji Bao Dao·2026-01-05 23:07

Core Insights - The Chinese innovative pharmaceutical industry is transitioning from scale expansion to value enhancement, facing challenges such as market saturation and homogeneous competition [2] - Companies need to focus on innovative solutions that address unmet clinical needs rather than following trends [3] Company Strategy - The company adopts a "two-pronged" strategy, balancing traditional validated targets with innovative products to ensure stable revenue while pursuing high-value innovations [4] - Current research focuses on three core areas: infectious diseases, metabolic diseases, and oncology, with a particular emphasis on unmet clinical needs [4] Response to Market Challenges - The company recognizes that a crowded market wastes resources and emphasizes the need for innovative approaches, such as combining existing targets for new therapeutic directions [6] - The company is advancing its anti-fibrotic drug, HEC585, for idiopathic pulmonary fibrosis (IPF), showing significant clinical trial results that outperform competitors [6][7] AI in Drug Development - The company has developed an AI drug discovery platform that leverages over 20 years of laboratory data, enhancing the efficiency of drug development processes [8] - AI has significantly reduced the time required for drug development, exemplified by a project that entered clinical trials 50% faster due to AI integration [9] International Expansion - The trend of Chinese innovative drugs entering international markets is increasing, driven by improved R&D capabilities and the need for broader market access [12] - The company is actively pursuing international collaborations and has made significant progress in preparing its products for the U.S. market [13][14] Market Positioning - The company emphasizes the importance of addressing both clinical and market needs, focusing on high-prevalence diseases with limited treatment options to align with policy support [16] - The company’s strategy includes leveraging its strengths in specific therapeutic areas while planning for international market entry [16]