What to Expect From Eli Lilly’s Q4 2025 Earnings Report

Company Overview - Eli Lilly and Company (LLY) has a market cap of $1 trillion and is a leading global research-based pharmaceutical company, founded in 1876 and headquartered in Indianapolis, Indiana. The company offers a wide range of prescription medicines, including treatments for type 2 diabetes, weight management, cancer, autoimmune conditions, and established insulin therapies [1] Earnings Expectations - Analysts anticipate Eli Lilly to report Q4 earnings of $7.47 per share, representing a 40.4% increase from $5.32 per share in the same quarter last year. The company has surpassed Wall Street's EPS estimates in three of the last four quarters [2] - For fiscal 2025, the expected EPS is $23.95, an 84.4% increase from $12.99 in fiscal 2024, with a projected rise to $33.59 in fiscal 2026, reflecting a 40.3% annual growth [3] Stock Performance - Eli Lilly's stock has increased by 35.1% over the past 52 weeks, outperforming the S&P 500 Index's 19.7% gains and the S&P 500 Healthcare Sector SPDR's 12.7% returns during the same period [4] Strategic Developments - On January 7, Eli Lilly's shares rose by 3.3% following the announcement of a strategic partnership with Nimbus Therapeutics to develop an oral obesity treatment, which includes a $55 million upfront payment and potential milestone payments of up to $1.3 billion. Additionally, the company is in advanced talks to acquire Ventyx Biosciences for over $1 billion, aimed at enhancing its drug portfolio and reinforcing its position in the weight-loss therapeutics market [5] Analyst Consensus - The consensus opinion on Eli Lilly stock is "Strong Buy," with 22 out of 27 analysts recommending a "Strong Buy," two suggesting a "Moderate Buy," and three advising a "Hold." The average analyst price target for Eli Lilly is $1,161.76, indicating a potential upside of 7.5% from current price levels [6]