中医药抗衰老获重大突破！以岭药业八子补肾胶囊入选“2025长寿医学十大进展”

Core Insights - The "2025 Longevity Medicine Top Ten Advances" conference highlighted the inclusion of the patented traditional Chinese medicine Ba Zi Bu Shen capsule, marking a significant breakthrough in anti-aging research and application in traditional Chinese medicine [1][8]. Group 1: Theoretical Innovations - The core achievement recognized is the "Qi-Luo Theory and Jing-Qi-Shen Theory" guiding anti-aging research, which integrates traditional Chinese medicine with modern biological findings on aging [3]. - The research identifies "kidney essence deficiency - vital energy deficiency - spirit and form depletion" as the core pathogenesis of aging, establishing an integrated intervention strategy [3]. Group 2: Fundamental Research Achievements - The research under the Qi-Luo Theory has produced systematic and original results, addressing multiple internationally recognized aging markers, with findings published in reputable journals [4]. - A study published in Biomedicine & Pharmacotherapy demonstrated that Ba Zi Bu Shen capsule significantly improves memory and muscle endurance in naturally aging mice, reversing age-related methylation changes and extending healthy lifespan [4]. Group 3: Mechanisms of Action - Ba Zi Bu Shen capsule has been shown to reduce the accumulation of aging cells in the brain, enhance neurogenesis, and improve cognitive function through various mechanisms [5]. - The capsule promotes muscle health by inhibiting the aging of bone marrow mesenchymal stem cells and enhancing muscle cell differentiation, effectively combating muscle atrophy [5]. - It activates the KEAP1-NRF2 antioxidant pathway to mitigate skin aging and improves vascular health by upregulating longevity protein SIRT3, reducing endothelial cell aging [6]. Group 4: Clinical Efficacy - A large-scale, randomized, double-blind, placebo-controlled clinical study involving 530 participants demonstrated that Ba Zi Bu Shen capsule significantly alleviates core aging symptoms and improves quality of life [7]. - In the elderly subgroup, the capsule showed clear benefits in enhancing physical function, with grip strength increasing by 12% and muscle mass by 8% [7]. Group 5: Strategic Implications - The research aligns with global efforts to address population aging, aiming to extend healthy lifespan and integrating traditional Chinese medicine with modern biological research [8]. - The recognition of this research in the "2025 Longevity Medicine Top Ten Advances" underscores its scientific and translational value, contributing to the national strategy for healthy aging [8].