NEW HOPE(SZ:000876) Jin Rong Jie·2026-01-27 07:56Group 1 - The Nipah virus has a high mortality rate of 40%-70% and has been a significant public health concern since its first outbreak in Malaysia in 1998 [1] - The frequency and geographical spread of Nipah virus outbreaks in India and Bangladesh are increasing, with recent cases reported in January 2026 [1] - The World Health Organization (WHO) has classified Nipah virus as a top priority regional threat due to its high fatality rate and lack of approved treatments or vaccines [1] Group 2 - VV116 is a new oral nucleoside antiviral drug that has shown significant antiviral activity against the Nipah virus in vitro and in animal models [2] - In a study, VV116 increased the survival rate of infected golden hamsters to 66.7% at a dosage of 400 mg per kg body weight, while significantly reducing viral loads in target organs [2] - The research indicates that VV116 could serve as a preventive treatment for high-risk groups and provide a ready option for addressing current and future Nipah virus outbreaks [2]