益方生物拟调整募投项目内部投资结构，聚焦核心管线研发

Core Viewpoint - The company has approved an internal restructuring of its fundraising investment projects to optimize the investment structure for its "new drug research and development projects" while keeping the total fundraising amount unchanged [1] Investment Structure Adjustment - The company will add the preclinical candidate drug "YF550" as a sub-project and reallocate funds among various sub-projects [1] - An additional investment of 232.1095 million yuan will be allocated to the oral TYK2 inhibitor D-2570 project to advance clinical trials for multiple autoimmune diseases, including psoriasis and ulcerative colitis [1] - New investments of 47.2 million yuan, 42.9 million yuan, and 20 million yuan will be made for the preclinical projects YF087, YF550, and exploratory research, respectively [1] - Funding for the URAT1 inhibitor D-0120 project will be reduced by 342.2095 million yuan [1] Strategic Focus - The adjustments aim to concentrate resources on core pipelines with faster research and development progress and greater market potential to enhance funding efficiency and accelerate product development [1] - The proposal is subject to approval at the company's shareholder meeting [1]