InventisBio (SH:688382) Xin Lang Cai Jing·2026-02-26 10:25Core Viewpoint - The company, Yifang Biopharma (688382.SH), expects to achieve a revenue of 373.25 million yuan for the fiscal year 2025, while projecting a net loss of 317 million yuan attributable to the parent company [1]. Group 1: Financial Performance - For the fiscal year 2025, the company anticipates a revenue of 373.25 million yuan and a net profit loss of 317 million yuan [1]. - The company will continue to experience losses in 2025 due to high R&D expenditures that cannot be covered by current technology licensing and cooperation income [2]. Group 2: R&D Progress - The company has made significant progress in its R&D pipeline, with several core clinical projects entering critical stages [1]. - The oral selective estrogen receptor degrader (SERD) D-0502 is undergoing Phase III clinical trials for second-line treatment in China [1]. - The TYK2 inhibitor D-2570 has initiated clinical explorations in multiple autoimmune disease areas, including ongoing Phase II trials for ulcerative colitis and Phase III trials for psoriasis in China, as well as a Phase I trial in the United States [1]. - The URAT1 inhibitor D-0120 has completed follow-up for its Phase II clinical trial in the U.S., with all research expected to be completed by Q1 2026 [1]. - The company is also advancing two innovative preclinical candidates, WRN inhibitor YF087 and KIF18A inhibitor YF550, which have shown promising anti-tumor potential in preclinical studies and are currently undergoing IND supportive research [2]. - The company continues to invest in early-stage R&D, including the development of other candidate drugs and the establishment of innovative technology platforms for long-term growth [2].