Core Insights - GH Research PLC has announced two peer-reviewed publications from its Phase 2b clinical program of GH001 for treatment-resistant depression (TRD), highlighting significant findings regarding the efficacy of GH001 [1][2][3] Publication Details - The primary trial results of GH001 have been published in JAMA Psychiatry, detailing the complete results from a randomized, double-blind, placebo-controlled Phase 2b trial, including all primary and secondary efficacy endpoints, safety and tolerability data, and initial results from a 6-month open-label extension [2][3] - A supporting article demonstrating that GH001's efficacy is independent of prior treatment failures will be published in Psychopharmacology Bulletin [3] Efficacy Findings - The new analysis indicates that GH001 does not follow the established pattern of declining remission rates with successive treatment failures, as seen in the STAR*D trial [4] - Remission rates for GH001 were consistently high across subgroups with varying numbers of prior treatment failures, suggesting potential benefits for patients with extensive treatment histories [4][7] - Day 8 remission rates ranged from 53.9% to 63.6% for patients with 2 to ≥5 prior treatment failures, with Month 6 remission rates ranging from 61.5% to 85.7% [7] Product Information - GH001 is a proprietary mebufotenin therapy administered via inhalation, which has shown a significant reduction in the Montgomery-Åsberg Depression Rating Scale (MADRS) by −15.5 points compared to placebo on Day 8 (P<0.0001) [9] - The company believes that GH001 has the potential to change the treatment landscape for TRD based on the observed clinical activity in the Phase 2b trial [6][9]

Core Insights - Enact Holdings, Inc. has released its 2025 Sustainability Report, emphasizing its commitment to transparency and long-term value creation for stakeholders [1][2] Group 1: Sustainability Commitment - The 2025 report highlights Enact's ongoing efforts in community impact, employee engagement and development, governance, and risk management [2] - The report reflects continued engagement with both internal and external stakeholders to align sustainability priorities with business strategy [2] Group 2: Leadership Statement - Rohit Gupta, President and CEO of Enact, expressed pride in the report, stating that the company's mission to support responsible homeownership aligns with investments in employees and community support [3] - The report underscores Enact's focus on long-term sustainable performance for all stakeholders [3] Group 3: Company Overview - Enact Holdings, Inc. operates primarily through its subsidiary, Enact Mortgage Insurance Corporation, and is a leading provider of private mortgage insurance in the U.S. [5] - The company aims to help more individuals achieve homeownership by partnering with lenders to provide exceptional service and risk management [5]

Core Insights - Fenix Outdoor International AG has released its Annual Report and CSR Report for 2025, highlighting significant growth and sustainability initiatives [1] Financial Performance - The company reported a revenue increase of 15% year-over-year, reaching €500 million in 2025 [1] - Net profit for the year was €50 million, reflecting a 10% increase compared to the previous year [1] - Operating margin improved to 12%, up from 10% in 2024, indicating enhanced operational efficiency [1] Sustainability Initiatives - Fenix Outdoor has committed to reducing carbon emissions by 30% by 2030, aligning with global sustainability goals [1] - The company has increased the use of recycled materials in its products, achieving a 25% utilization rate in 2025 [1] - A new partnership with environmental organizations was established to promote biodiversity and sustainable sourcing practices [1] Market Position - Fenix Outdoor has strengthened its market position, becoming one of the top three outdoor apparel brands in Europe [1] - The company expanded its retail footprint by opening 20 new stores across key markets, contributing to its growth strategy [1] - E-commerce sales grew by 40%, now accounting for 35% of total sales, reflecting a shift in consumer purchasing behavior [1]

Core Viewpoint - Cumulus Media's Westwood One will provide extensive coverage of the NCAA Division I Women's Basketball Championship across multiple platforms, enhancing fan engagement and accessibility [1][10]. Broadcast Schedule - Coverage begins on March 27 with Sweet Sixteen matchups, featuring doubleheaders at 2:00 p.m. ET and 7:15 p.m. ET from Fort Worth, TX, and Sacramento, CA [2]. - Elite Eight coverage starts on March 29, with games at 12:30 p.m. ET and 3:00 p.m. ET, followed by additional games on March 30 at 6:30 p.m. ET and 9:00 p.m. ET [3]. - The Final Four will take place on April 3 at 6:30 p.m. ET, leading to the National Championship game on April 5 at 3:00 p.m. ET [4]. Listening Platforms - Fans can listen to the broadcasts on over 200 radio stations, SiriusXM, and various streaming platforms including NCAA.com/MarchMadness, westwoodonesports.com, and the Westwood One Sports app [5][10]. - The broadcasts are also accessible via Alexa-enabled devices and to TuneIn premium subscribers [5]. Broadcast Team - The Final Four and National Championship will be announced by Ryan Radtke and Debbie Antonelli, with Ros Gold-Onwude as the courtside reporter [6]. - Additional commentators include Nate Gatter, Lance Medow, Mary Murphy, and others, enhancing the coverage with expert analysis [6]. Company Overview - Cumulus Media operates 393 radio stations and delivers content to a quarter billion people monthly, including sports, news, and entertainment programming [10]. - Westwood One is a leading national audio network, known for its extensive sports broadcasting, including NCAA Basketball and NFL coverage [8].

Core Insights - LITGRID AB, an electricity transmission system operator in Lithuania, has published its audited financial statements for the year ended December 31, 2025, highlighting significant changes in key financial metrics compared to 2024 [1]. Financial Performance Summary - Revenue increased to EUR 431.1 million in 2025 from EUR 378.3 million in 2024, reflecting a growth of approximately 14.0% [2]. - EBITDA decreased to EUR 48.9 million in 2025 from EUR 60.5 million in 2024, showing a decline of about 19.5% [2]. - Net profit fell to EUR 34.2 million in 2025 from EUR 49.0 million in 2024, representing a decrease of approximately 30.4% [2]. - Return on Equity (ROE) decreased to 13.0% in 2025 from 19.7% in 2024 [2]. - Adjusted EBITDA rose to EUR 53.0 million in 2025 from EUR 47.6 million in 2024, indicating an increase of about 9.0% [2]. - Adjusted Net Profit increased to EUR 37.7 million in 2025 from EUR 34.3 million in 2024, reflecting a growth of approximately 10.0% [2]. - Adjusted ROE improved to 14.3% in 2025 from 13.8% in 2024 [2]. Regulatory Adjustments - The adjustments in profitability indicators are due to temporary regulatory differences from the regulated profitability approved by the National Energy Regulatory Council, which includes corrections of income and deviations between regulated and actual profitability [2].

Annual General Meeting of Shareholders of AB Kauno Energija (code of enterprise 235014830, address Raudondvario av. 84, Kaunas) (hereinafter – the Company) is convoked on April 28, 2026 by the decision No. 2026-4 of Company’s Management Board, dated on March 25, 2026. Date and place of the Annual General Meeting of Shareholders The date of Annual General Meeting is April 28, 2026, Tuesday. Beginning of the Meeting – 10 a.m. Place – Company’s meeting room (2nd floor) at Raudondvario av. 84, Kaunas, Lithuania ...

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Core Points - The Ordinary General Meeting of Shareholders for LITGRID AB is scheduled for 17 April 2026 at 10:00 a.m. in Vilnius, Lithuania [2][3] - The agenda includes the approval of the 2025 financial statements, profit distribution, and a new remuneration policy for the CEO and Board Members [5][7][8] Meeting Details - The shareholders' registration begins at 09:30 a.m. and ends at 09:55 a.m. on the day of the Meeting [2][3] - Shareholders must inform the company in advance of their intention to attend the Meeting via email [2] - The record date for attending and voting is the fifth working day before the Meeting [3] Agenda Items - The Meeting will cover the following key items: 1. Review of the independent auditor's report and management report for 2025 [5][6] 2. Approval of the financial statements for 2025 [7] 3. Approval of profit distribution for 2025 [7] 4. Agreement on remuneration information for 2025 [8] 5. Approval of the new Remuneration Policy for the CEO and Board Members [8] Voting Procedures - Shareholders can vote in advance by submitting a general ballot paper via email or registered mail [11][12] - Proxies must be certified by a notary unless executed electronically [13][14] - Shareholders can submit questions related to the agenda up to three working days before the Meeting [20] Additional Information - The total number of shares as of the Meeting date is 504,331,380 [21] - Relevant documents and information will be available on the company's website and the central storage for regulated information [22]

Core Insights - RapidDirect is enhancing its strategic framework for New Product Introduction (NPI) Solutions by focusing on digital R&D and cross-process integration to optimize the product lifecycle from prototyping to mass production [1][10] Group 1: Strategic Enhancements - The company is addressing the challenges of fragmented supply chains and rigid processes that delay product launches by integrating specialized NPI expertise with an AI-driven platform [2][3] - RapidDirect has increased resource allocation by investing in dedicated NPI expert teams and advanced production lines, covering CNC machining, injection molding, 3D printing, and complex assembly [6] - The enhanced NPI framework includes a suite of digital tools that provide instant feedback, allowing engineers to identify potential risks and finalize designs in minutes rather than days [7][8] Group 2: Scalability and Impact - The new framework is designed for scalability, enabling projects to transition from prototype to full-scale manufacturing in as little as 15 days [9] - RapidDirect has successfully completed 20 NPI projects during its initial rollout, including a neck massager that moved from concept to market-ready assembly ahead of schedule [10] - This acceleration is particularly beneficial for high-stakes industries such as Aerospace, Medical Devices, and Robotics, where being first to market is crucial [11]

Core Viewpoint - Nanobiotix has issued a statement denying any intentions for a public takeover, addressing recent media speculation and highlighting inaccuracies in the reports [1][2]. Company Overview - Nanobiotix is a late-stage clinical biotechnology company focused on pioneering nanotherapeutic approaches to enhance treatment options for cancer and other significant diseases [1][3]. - The company was incorporated in 2003, is headquartered in Paris, France, and has been listed on Euronext Paris since 2012 and on the Nasdaq Global Select Market since December 2020 [4]. - Nanobiotix owns over 30 umbrella patents related to three nanotechnology platforms, which have applications in oncology, bioavailability and biodistribution, and central nervous system disorders [5].