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Rakovina Therapeutics KT-5000AI Program Yields Potent ATR Inhibitor Hits in Early Screening
Globenewswire· 2025-07-23 08:00
Compounds developed through collaboration with Variational AI show targeted activityVANCOUVER, British Columbia, July 23, 2025 (GLOBE NEWSWIRE) -- Rakovina Therapeutics Inc. (“Rakovina” or the “Company”) (TSX-V: RKV) (FSE: 7JO0), a biopharmaceutical company advancing next-generation cancer therapies through artificial intelligence (AI)-powered drug discovery, today announced meaningful progress in its AI-driven KT-5000AI program, advancing the development of precision ATR (Ataxia Telangiectasia and Rad3-rel ...
Flutter announces launch of offering of Additional Senior Secured Notes due 2031
Globenewswire· 2025-07-23 07:30
Core Viewpoint - Flutter Entertainment plc is launching an offering of senior secured notes in multiple currencies to fund strategic acquisitions and partnerships, indicating a proactive approach to growth and market positioning [1][3]. Group 1: Offering Details - Flutter is offering USD, EUR, and GBP-denominated senior secured notes due in 2031, which will be a further issuance of previously issued notes [1]. - The total amount intended to be raised through the notes and an incremental debt facility is $1,755 million [3]. Group 2: Purpose of Funds - Proceeds from the offering will be used to acquire a 5% minority interest in FanDuel and to extend a strategic partnership with Boyd Interactive Gaming Holdings, L.L.C. [3]. Group 3: Company Overview - Flutter is recognized as a leading online sports betting and iGaming operator globally, with a strong market presence in the US [4]. - The company operates a diverse portfolio of brands, including FanDuel, Sky Betting & Gaming, and PokerStars, among others [5].
21Shares Partners with Societe Generale to Expand Institutional Access to Crypto ETPs in Europe
Globenewswire· 2025-07-23 07:00
Societe Generale to act as market maker for 21Shares’ Bitcoin and Ethereum ETPs on key German and Eastern Europe fund platforms, expanding institutional access to crypto Zurich, 23 July 2025 – 21Shares AG, one of the world’s leading issuers of cryptocurrency exchange-traded products (ETPs), is pleased to announce it has entered into an ETP market making fund platform agreement with Societe Generale, a leading institutional player in exchange traded products, to enhance liquidity across 21Shares ETPs on fund ...
Dentsu Expands Partnership with Magnite to Streamline CTV and Video Activation Across EMEA
Globenewswire· 2025-07-23 07:00
Core Insights - Magnite has announced a strategic partnership with dentsu in EMEA to enhance innovation and performance in the media supply chain [1][2] - The collaboration focuses on utilizing Magnite's video tools to support dentsu's Total TV initiative and aims to lead in the "Algorithmic Era" of advertising [1][3] Group 1: Partnership Details - The partnership enables dentsu to leverage Magnite's SpringServe video platform for more efficient and data-rich connections to inventory, enhancing media experiences [2] - The collaboration emphasizes a commitment to evolving media deployment and optimization, with a focus on client performance [2] Group 2: Strategic Goals - Dentsu aims to build Next Gen media solutions through partnerships with leading technologies, enhancing client success in the Algorithmic Era [3] - Magnite's technology facilitates a shift from transactional media buying to a more curated, high-performance approach, providing greater visibility and control over media buys [3]
EXEL Industries: Q3 2024-2025 revenue down 10.9%
Globenewswire· 2025-07-23 06:03
Core Viewpoint - EXEL Industries Group reported a revenue decline of 10.9% in Q3 2024-2025, primarily due to lower volumes in Agricultural Spraying and foreign exchange impacts from the depreciation of the dollar [3][10]. Revenue Breakdown - **Agricultural Spraying**: Revenue decreased by €36.7 million (-24.2%) in Q3 compared to the previous year, with significant declines in Australia, North America, and France, while Northern and Central Europe showed slight growth [2][4]. - **Sugar Beet Harvesting**: Sales fell by €3.3 million (-8.5%), with new machine sales slightly increasing but not compensating for the decline in used machines [2][5]. - **Leisure**: Revenue increased by €3.9 million (+7.3%), driven by favorable weather conditions, particularly in the United Kingdom [2][6]. - **Industry**: Sales grew by €1.7 million (+2.3%), supported by strong performance in Systems projects and traditional paint application ranges, with varied geographical performance [2][7]. Nine-Month Sales Overview - **Agricultural Spraying**: Total sales for the nine-month period were €310.0 million, down €90.1 million (-22.5%) [2]. - **Sugar Beet Harvesting**: Nine-month sales were €80.2 million, a decrease of €3.2 million (-3.8%) [2]. - **Leisure**: Revenue reached €118.1 million, an increase of €5.7 million (+5.1%) [2]. - **Industry**: Sales totaled €217.3 million, up €3.8 million (+1.8%) [2]. - **Overall Group Revenue**: The total revenue for the nine-month period was €725.5 million, down €83.8 million (-10.4%) [2]. Management Commentary - The CEO noted that the revenue results were in line with expectations, and the company is adapting its cost structure to address the decline in agricultural volumes while maintaining vigilance on tariff policies in North America [10][11]. - The order book has begun to stabilize after two years of decline, indicating potential recovery [11]. Future Outlook - The company anticipates stable sales in Western Europe and growth in North America, contingent on favorable tariff policies [12]. - The modernization of the Stains plant in France is ongoing and expected to be operational by autumn 2025 [12].
CoinShares Asset Management Becomes First Continental European Regulated Asset Manager to Receive MiCA Authorisation
Globenewswire· 2025-07-23 06:00
Core Insights - CoinShares International Limited has become the first major European asset manager to receive authorisation under the Markets in Crypto-Assets (MiCA) Regulation, marking a significant milestone in the European digital asset industry [1][4] - This authorisation allows CoinShares to offer comprehensive investment services across all asset classes throughout the European Union, positioning the firm uniquely in the market [2][6] Regulatory Achievements - CoinShares is now the only asset management firm in continental Europe with a combination of AIFM, MiFID, and MiCA licenses, enabling it to provide institutional-grade portfolio management services [2][7] - The MiCA authorisation addresses a critical gap in the European crypto investment landscape, ensuring proper licensing and organisational structure for asset management [3][4] Market Positioning - The regulatory framework positions CoinShares as a leader in professional active management services for both traditional and digital assets, with a commitment to governance and accountability [5][8] - CoinShares operates under multiple regulatory bodies, including the Jersey Financial Services Commission and the Autorité des marchés financiers in France, enhancing its credibility in the market [9]
RIBER: 2025 FIRST-HALF BUSINESS - FULL-YEAR REVENUES EXPECTED TO EXCEED €40M
Globenewswire· 2025-07-23 06:00
2025 FIRST-HALF BUSINESS FULL-YEAR REVENUES EXPECTED TO EXCEED €40M Bezons, July 23, 2025 - 8:00am - RIBER, the global leader in Molecular Beam Epitaxy (MBE) equipment for the semiconductor industry, reports its revenues for the first half of 2025. Business developments At June 30 (€m)20252024ChangeSystems7.89.4-17%Services and accessories3.04.3-31%Total half-year revenues 10.713.7-22% ...
KPN delivers a strong quarter; full-year 2025 outlook raised
Globenewswire· 2025-07-23 05:30
Group 1 - The company reported a continued growth in Group service revenue of 3.7% year-on-year, driven by all segments [2] - Consumer service revenues increased by 1.3% year-on-year, with solid commercial momentum in Consumer broadband (13,000 new subscribers) and postpaid (37,000 new subscribers) [2] - Business service revenue growth remains high at 5.7% year-on-year, supported by all divisions [2] Group 2 - Adjusted EBITDA AL increased by 6.4% year-on-year in Q2 2025, with contributions of 1.4% from IPR benefits and 1.0% from Althio [2] - The first half of Free Cash Flow reached €309 million, progressing according to plan [2] - The company leads the Dutch fiber market, now covering two-thirds of the Netherlands [2] Group 3 - The full-year 2025 outlook has been raised to over €2,630 million in adjusted EBITDA AL and over €940 million in Free Cash Flow, reflecting both IPR benefits and solid underlying progress [2]
Alstom S.A: Alstom’s first quarter 2025/26: Commercial momentum off to a good start, outlook confirmed
Globenewswire· 2025-07-23 05:30
Core Insights - Alstom reported strong commercial performance in Q1 2025/26, with orders exceeding €4 billion and a positive outlook for future sales driven by North American momentum and projects in Germany [4][11]. Group Performance - Orders received in Q1 2025/26 amounted to €4.1 billion, an increase of 11.8% compared to €3.645 billion in the same period last year, with organic growth at 13.6% [3][6]. - Sales reached €4.5 billion, reflecting a 2.8% increase year-over-year, with organic sales growth of 7.2% [9][11]. Backlog and Future Visibility - As of June 30, 2025, Alstom's backlog stood at €92.3 billion, indicating strong visibility for future sales [2]. Geographic and Product Breakdown - Europe accounted for 85% of total order intake, with significant contracts including €1.7 billion for additional RER NG trainsets in France and €720 million for Coradia Stream trains in Bulgaria [7][8]. - In terms of sales, Rolling Stock generated €2.416 billion, up 3% reported and 5% organic, while Services reported stable sales of €1.070 billion [9][10]. Key Projects and Deliveries - Alstom delivered key milestones across various regions, including the first metro train for Grand Paris Express and the first Innovia automated people mover in the U.S. [12].
Ipsen announces changes to its Executive Committee
Globenewswire· 2025-07-23 05:30
Core Insights - Ipsen announced changes to its Executive Committee, effective September 1, 2025, with Mari Scheiffele, Andreas Gerber, and Caroline Sitbon taking on new roles [1][5][7] Group 1: Executive Appointments - Mari Scheiffele will transition from leading commercial operations in the International Region to overseeing all medicines in Oncology and Rare Disease, focusing on product development and pipeline innovation [2][5] - Andreas Gerber joins Ipsen from Johnson & Johnson as Head of International, responsible for operations outside North America, leveraging his experience in Oncology to drive growth in Ipsen's therapeutic areas [3][5] - Caroline Sitbon has been promoted to General Counsel, leading legal and business ethics, and will also serve as the General Secretary of the Board of Directors [4][5] Group 2: Leadership Perspectives - CEO David Loew expressed confidence in the new appointments, highlighting the combination of internal promotions and new leadership as a strength for Ipsen's ongoing transformation [5] - Mari Scheiffele emphasized her commitment to innovation and excellence in her new role [5] - Andreas Gerber expressed enthusiasm for leading the International Region and making a positive impact on patients' lives [5] - Caroline Sitbon conveyed her excitement about ensuring compliance and integrity within the organization [5] Group 3: Company Overview - Ipsen is a global biopharmaceutical company focused on transformative medicines in Oncology, Rare Disease, and Neuroscience, with nearly 100 years of development experience [6][8] - The company operates in over 40 countries and provides medicines to patients in more than 80 countries [8]