Investment Rating - The report maintains an "Outperform" rating for BeiGene with a target price of HK141.00 [2][6]. Core Insights - In Q1 2025, BeiGene achieved revenue of USD1.12 billion, a year-on-year increase of 48.6%, with product revenue at USD1.11 billion. The net income attributable to shareholders was USD1.27 million, marking the first quarterly recurring business profit under US GAAP [3][13]. - The growth in overseas revenue, particularly from BRUKINSA, was a significant driver for the company's turnaround to profitability [4][14]. - The management has maintained its full-year revenue guidance of USD4.9 billion to USD5.3 billion, indicating confidence in future performance [3][13]. Financial Performance Summary - Revenue projections for the upcoming years are as follows: USD5.01 billion in FY2025, and USD6.03 billion in FY2026, reflecting growth rates of 31% and 20% respectively [11]. - The net profit is expected to turn positive in FY2025 with a forecast of USD34 million, and further increase to USD390 million in FY2026, showing a significant recovery from previous losses [11]. - Gross profit margin (GPM) is projected to improve slightly from 84.7% in FY2025 to 85.0% in FY2026 [11]. Product Performance - BRUKINSA generated revenue of USD790 million in Q1 2025, a year-on-year increase of 62.1%. The U.S. sales reached USD563 million, while European sales were USD116 million, indicating strong international demand [4][14]. - The report highlights that BRUKINSA's terminal sales in hospitals increased by 9.2% quarter-on-quarter, suggesting continued growth potential [4][14]. Expense Management - The report notes continuous optimization of expense ratios, with a gross profit margin of 85.2% in Q1 2025, up by 1.9 percentage points year-on-year. R&D expenses were USD482 million, with a reduced R&D expense ratio of 43.1% [5][15]. - Operating profit improved to USD11.1 million in Q1 2025, compared to a loss of USD261 million in the same quarter of the previous year [5][15].
百济神州（06160）：1Q25业绩：利润端实现扭亏，符合预期