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恒瑞医药(01276):公司创新药管线海外权益授权给GSK,将显著增厚利润

Investment Rating - The report assigns a "Buy" rating to the company, indicating a potential upside of 15% to 35% [12]. Core Insights - The company has entered into an agreement with GSK for the global exclusive rights to the HRS-9821 project and up to 11 additional projects, which is expected to significantly enhance profits. GSK will pay an upfront fee of $500 million, with potential milestone payments totaling approximately $12 billion based on successful development and sales [6][9]. - HRS-9821 is a potential best-in-class PDE3/4 inhibitor currently in Phase I clinical development for treating chronic obstructive pulmonary disease (COPD). The global market for similar products is growing, with a significant patient population in China [9]. - The company has accelerated its business development (BD) transactions, indicating a recognition of its innovative research capabilities by large multinational pharmaceutical companies. This is expected to lead to a revaluation of its pipeline [9]. - The profit forecast for 2025 has been raised due to the upfront payment, with projected net profits of RMB 10.1 billion, reflecting a year-on-year increase of 59.3% [9][11]. Financial Summary - The company’s projected net profits for 2025-2027 are RMB 10.1 billion, RMB 8.75 billion, and RMB 10.4 billion, respectively, with year-on-year growth rates of 59.3%, -13.3%, and 18.9% [11]. - Earnings per share (EPS) are expected to be RMB 1.52, RMB 1.32, and RMB 1.56 for the years 2025-2027, with corresponding year-on-year growth rates of 52.1%, -13.3%, and 18.9% [11]. - The company’s revenue is projected to grow from RMB 36.06 billion in 2025 to RMB 45.40 billion in 2027, with a steady increase in operating profit [14].