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君实生物(688180):2025H1特瑞普利单抗销售稳健增长,PD-1/VEGF双抗进入II期临床
Tianfeng Securities·2025-10-08 06:13

Investment Rating - The report maintains a "Buy" rating for the company, indicating an expected relative return of over 20% within the next six months [5]. Core Insights - The company reported a revenue of 1.168 billion yuan for H1 2025, representing a year-on-year growth of 48.64%. The net loss was 413 million yuan, a reduction in loss of 36.01% compared to the previous year [1]. - The sales revenue of the company's core product, Tislelizumab, in the domestic market reached approximately 954 million yuan in H1 2025, showing a year-on-year increase of about 42%. The product has received approval for 12 indications, with four new indications added to the medical insurance directory in 2025 [2]. - The PD-1/VEGF dual antibody, JS207, is currently in Phase II clinical trials, demonstrating strong anti-tumor activity in preclinical studies. It is being explored in various tumor types in combination with other therapies [3]. - The company has a rich pipeline of oncology drugs, with the anti-BTLA monoclonal antibody, Tifcemalimab (JS004), currently in Phase III clinical trials for LS-SCLC, having enrolled nearly 400 patients [4]. Financial Summary - The company's revenue projections for 2025 and 2026 have been revised down to 2.584 billion yuan and 3.441 billion yuan, respectively. The expected net loss for 2025 is adjusted to 675 million yuan [5]. - The company’s total market capitalization is approximately 31.77 billion yuan, with a total share capital of 766.39 million shares [6]. - The earnings per share (EPS) is projected to improve from -2.32 yuan in 2023 to 0.18 yuan in 2027, indicating a potential turnaround in profitability [9].