医药行业周报（25/11/10-25/11/14）：从Arrowhead管线看小核酸发展方向-20251119

Investment Rating - The report maintains a "Positive" investment rating for the pharmaceutical industry [3][47]. Core Views - The pharmaceutical index increased by 3.29% from November 10 to November 14, outperforming the CSI 300 index by 4.37%. The report suggests focusing on core innovative drug assets and companies with clear performance trends [4][17]. - Arrowhead Pharmaceuticals is highlighted for its strong pipeline in RNAi therapies, particularly its TRiM platform, which targets various diseases and has shown significant stock price appreciation [7][8]. - The report emphasizes the ongoing transformation in the Chinese pharmaceutical industry, with a shift towards innovation and international expansion, driven by aging demographics and increasing healthcare demands [35][36]. Summary by Sections Arrowhead Pipeline Progress - Arrowhead Pharmaceuticals has a robust pipeline focusing on targeted siRNA drugs, with significant advancements in cardiovascular and neurological diseases. The stock price has surged by 313% since its lowest point in 2025 [7][8]. - Key products include Plozasiran, which is expected to significantly reduce triglyceride levels and is pending FDA approval [12][13]. Industry Perspective - The report underscores the importance of innovative drugs as a primary investment theme for the year, with a focus on manufacturing, international expansion, and aging consumer demographics [17][35]. - The pharmaceutical index has shown a year-to-date increase of 22.09%, indicating strong market performance [17][24]. Investment Recommendations - Suggested stocks include innovative drug companies such as Xinyi Tai, Sanofi, and China Biopharmaceuticals, as well as companies in the medical device sector like Mindray and United Imaging [39][36]. - The report also highlights the potential for growth in sectors related to aging populations and outpatient consumption, recommending companies like Kunming Pharmaceutical and Yuyue Medical [38][36].