医药生物：生物安全法案出现积极变化，重视CXO机会！

Investment Rating - The industry rating is "Outperform the Market" [7][76] Core Insights - The report emphasizes the importance of external demand-driven CXO investment opportunities due to the recent interest rate cuts by the Federal Reserve and the elimination of policy uncertainties related to the new Biosecurity Act [4][29] - The report highlights a mixed performance in the pharmaceutical sector, with a notable focus on innovative drugs and medical devices as key investment areas for the upcoming year [5][34] Summary by Sections Market Review - The CITIC Pharmaceutical Index fell by 1.1% during the week of December 8-12, 2025, underperforming the CSI 300 Index by 1.0 percentage points, ranking 15th among CITIC's primary industry classifications [3][34] - Year-to-date, the CITIC Pharmaceutical Biotech Index has risen by 15.6%, still underperforming the CSI 300 Index by 0.8 percentage points, ranking 16th [3][34] - Top-performing stocks for the week included Zhaoyan New Drug (+23.4%), Hotgen Biotech (+16.8%), and Haichuang Pharmaceutical (+13.9%) [3][53] Investment Opportunities - The Federal Reserve's recent interest rate cut is expected to improve overseas biotech investment and financing conditions, which will benefit CDMO (Contract Development and Manufacturing Organization) orders [4][21] - The new Biosecurity Act, which has passed the House and is awaiting Senate approval, is expected to have a limited impact on external demand for CXO companies, alleviating valuation pressures in the sector [4][28] Sector Performance - The pharmaceutical sector's overall valuation as of December 12, 2025, is 28.79, reflecting a slight decrease of 0.17, with a relative valuation premium of 12.02% compared to the broader market [44] - The total trading volume for the pharmaceutical sector during the week was 423.43 billion, accounting for 4.3% of the total A-share trading volume, with a 3.9% increase from the previous week [50][53]