Orient Securities·2026-03-15 09:43Investment Rating - The report maintains a "Positive" investment rating for the pharmaceutical and biotechnology industry in China [6] Core Viewpoints - The report emphasizes that semi-invasive brain-machine interfaces (BMIs) demonstrate significant safety advantages over invasive methods, making them more suitable for consumer applications [9][10] - The potential for semi-invasive BMIs to address safety concerns during implantation, long-term use, and removal is highlighted, suggesting a greater development potential [9][10] - The report identifies that the market for BMIs is expected to grow significantly, particularly in the treatment of neurological diseases, which will pave the way for future consumer-level applications [19][21] Summary by Sections 1. Semi-Invasive Surgery: Smaller Incisions and Shallow Implantation - Semi-invasive techniques are less invasive, reducing surgical risks compared to invasive methods [9][10] - The report notes that semi-invasive BMIs can achieve shallower implantation depths, minimizing damage to brain tissue [9][10] - The potential for algorithm advancements to further enhance implantation techniques is discussed [49] 2. Long-Term Safety and Higher Channel Limits - Semi-invasive BMIs do not form scar tissue, maintaining neuron integrity, which is crucial for long-term stability [51][57] - The report indicates that semi-invasive designs can avoid electrode displacement, which is a significant risk in invasive methods [61][67] - The ability of semi-invasive BMIs to manage thermal limits effectively is emphasized, allowing for higher channel counts without compromising safety [69][73] 3. Safer Removal and Greater Consumer Potential - The report highlights that removing semi-invasive electrodes poses less risk of damaging blood vessels compared to invasive electrodes [11][14] - The increasing frequency of hardware upgrades in BMIs necessitates safer removal methods, which semi-invasive designs can provide [11][14] - The report suggests that as the market for BMIs expands, semi-invasive methods will better meet consumer demands for easy replacement and upgrades [11][14] 4. Investment Recommendations and Targets - The report recommends focusing on semi-invasive BMI solutions with clear clinical progress and government support [14] - It suggests exploring companies within the semi-invasive BMI supply chain that show potential breakthroughs in the medical field and can extend into consumer markets [14]