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连发三篇论文:蓝晶微生物PHA工业化生产,突破文献最高产量与最低单位成本纪录
生物世界·2025-05-12 04:15

Core Viewpoint - Shanghai Blue Crystal Microbial Technology Co., Ltd. has achieved significant advancements in the production of polyhydroxyalkanoates (PHA) through innovative technologies, addressing both plastic pollution and carbon neutrality goals [2][24]. Group 1: Technological Innovations - The company developed the "Biohybrid" technology system, achieving the highest levels of unit yield, cost control, and carbon footprint management in PHA industrial production [4][9]. - A theoretical breakthrough was made in oil-based carbon source routes, with a maximum theoretical conversion rate of 130% and a reduced carbon source cost of $590 per ton, compared to traditional methods [6][8]. - The Biohybrid 1.0 technology improved PHA yield to 260 g/L in a 15-ton fermentation scale, enhancing production efficiency by 20% [11][15]. Group 2: Industrial Scale Achievements - Biohybrid 2.0 technology achieved a record PHA yield of 264 g/L and a 100% conversion rate of plant oil carbon sources at a 150-ton production scale [18][22]. - The integration of Biohybrid 1.0 and 2.0 technologies led to a stable production system with PHA yields exceeding 300 g/L and a carbon source conversion rate over 100% [22][30]. Group 3: Lifecycle Carbon Footprint Research - The company, in collaboration with Oxford University, published the first global study on the lifecycle carbon footprint of PHA, demonstrating a reduction of 64% compared to traditional petrochemical plastics [25][28]. - The study established a comprehensive lifecycle assessment model, revealing that using kitchen waste oil can further lower the carbon footprint to 2.01 kg-CO₂e/kg-Polymer [28][29]. Group 4: Economic Impact and Market Potential - The production cost of PHA has decreased by 41% since 2019, while unit yield has increased by 83%, positioning the company favorably for large-scale production of biodegradable materials [30].