突发！年内涨幅最大的指数暴跌6%！全市场超4400只个股下跌！泡泡玛特历史新高，市值首次突破3000亿！

Market Overview - The market experienced fluctuations, with the Shanghai Composite Index down 0.22%, Shenzhen Component Index down 0.72%, ChiNext Index down 0.96%, and the North Exchange 50 Index down 6.15% [1] - The total trading volume in the Shanghai and Shenzhen markets was 1.1 trillion, a decrease of 70.8 billion compared to the previous trading day [1] - Over 4,400 stocks declined, with banking stocks showing resilience, as several banks, including Shanghai Pudong Development Bank, reached historical highs [1] North Exchange 50 Index - The North Exchange 50 Index, which reached a historical high of 1500 points yesterday, saw a significant drop of over 6% today [4] - Leading stock Jinbo Biological, which has the highest market capitalization on the North Exchange, fell nearly 5%, with a current market value of 43.6 billion [7] - Jinbo Biological's stock price had been rising since March, peaking at 589.98 yuan per share on May 21, with a market value exceeding 52 billion [10] - The recent market adjustment is attributed to high-priced stocks retreating and signs of overbuying in micro-cap stocks [10] Innovative Drug Sector - The innovative drug sector showed strength, with Sanofi's stock rising for four consecutive days, achieving a 20% limit-up [11] - Sanofi announced a licensing agreement with Pfizer for its PD-1/VEGF dual-specific antibody SSGJ-707, with a record-breaking upfront payment of $1.25 billion [15] - The potential valuation of Sanofi is discussed, with estimates suggesting a significant increase in net profit due to the licensing agreement [16] Pop Mart - Pop Mart's market capitalization surpassed 300 billion Hong Kong dollars, with a stock price increase of over 5% on May 21 [17] - The surge in stock price is attributed to the strong global demand for its newly launched Labubu third-generation plush product, which has seen significant sales both domestically and internationally [21] - Morgan Stanley raised Pop Mart's target price from 204 HKD to 224 HKD, citing strong demand for Labubu v3 as a key growth factor [22]