锤娜丽莎暴瘦70斤！来看看中外顶流明星们的瘦身大法

Core Viewpoint - The article discusses the rising trend of weight loss among celebrities and public figures, highlighting the role of GLP-1 medications like Semaglutide and Tirzepatide in achieving significant weight loss results, with average reductions of 15% and 20% respectively. The impact of social media on public perception and awareness of weight loss is also emphasized [3][20][26]. Group 1: Celebrity Weight Loss Stories - Chinese singer and actress Chui Nalisah lost 70 pounds due to health concerns, specifically severe fatty liver disease, and emphasizes the importance of health over aesthetics [3][7]. - Elon Musk reported a weight loss of 30 pounds (approximately 27.2 pounds) using Semaglutide [8]. - Oscar winner Whoopi Goldberg shared her experience of using Tirzepatide to manage her weight after gaining due to steroid treatment [10]. - Grammy winner Kelly Clarkson attributed her slim figure to Semaglutide, alongside a high-protein diet and exercise [12]. - Jon Gosselin lost 32 pounds in two months after using Semaglutide, expressing regret for not starting earlier [14]. - Jeremy Clarkson began using Semaglutide after hearing positive feedback from others about its appetite-suppressing effects [16]. - Influencer Shannon Natalia lost approximately 20 kilograms with the help of Semaglutide while battling lipedema [18]. Group 2: Efficacy of Semaglutide - The STEP series of studies demonstrated that Semaglutide leads to an average weight loss of 15% in obese patients, significantly outperforming previous weight loss medications [20][25]. - In the STEP 1 study, participants lost an average of 14.9%, with over one-third losing more than 20% of their body weight [22]. - The STEP 2 study showed a 10.6% average weight reduction in patients with type 2 diabetes, with improvements in cardiovascular risk factors and quality of life [22]. - The STEP 3 study indicated a 16% weight loss when combined with behavioral therapy, compared to 5.7% in the placebo group [22]. - The STEP 4 study found that continuous use of Semaglutide resulted in an 18.2% weight loss over time [23]. - The STEP 7 study, focusing on a Chinese population, reported a 12.1% average weight loss with Semaglutide [23]. Group 3: Efficacy of Tirzepatide - The SURMOUNT-1 study showed that Tirzepatide significantly reduced weight in prediabetic patients, with average weight losses of 15.4% to 22.9% depending on dosage [26][28]. - The SURMOUNT-2 study confirmed a 15.7% average weight loss in type 2 diabetes patients using higher doses of Tirzepatide [28]. - The SURMOUNT-3 trial reported a weight loss of up to 26.6% after 72 weeks of treatment [30]. - The SURMOUNT-5 trial indicated that Tirzepatide outperformed Semaglutide, with participants losing an average of 50.3 pounds (22.8 kg) compared to 33.1 pounds (15.0 kg) for Semaglutide [30].