6种食物，让身体自产“司美格鲁肽”

Core Viewpoint - Semaglutide and Tirzepatide are breakthrough drugs for weight loss and diabetes management, targeting the underlying pathways of obesity and diabetes [1] Group 1: Mechanism of Action - The body produces natural versions of these drugs, known as incretin hormones, in the gut, which are regulated by nutrients and gut microbiota [2] - Specific bacteria in the lower gut convert indigestible food components into molecules that stimulate appetite and metabolism-controlling hormones like GLP-1, the natural version of Semaglutide [3] - GLP-1 and other hormones help regulate blood sugar through the pancreas and signal the brain about satiety, slowing down food movement in the digestive tract [3][4] Group 2: Impact of Processed Foods - The rise of processed foods has led to the removal of bioactive molecules like fiber and polyphenols, which are essential for regulating metabolic pathways [3] - The loss of these key food components and the resulting decline in gut microbiota diversity may significantly contribute to the increase in obesity and diabetes [6] Group 3: Dietary Recommendations - A healthy lifestyle, including regular exercise, stress management, sleep, outdoor activities, and a balanced diet, is crucial for managing metabolic diseases [5] - Introducing minimally processed foods rich in fiber and polyphenols can enhance GLP-1 levels and address the obesity and metabolic disease epidemic [5] Group 4: Foods that Stimulate GLP-1 Production - Eggs are rich in protein and monounsaturated fats, which can enhance GLP-1 secretion [8] - Nuts like almonds, pistachios, and peanuts may increase GLP-1 levels due to their protein, fiber, and healthy fat content [8] - High-fiber grains such as oats, barley, and whole wheat can stimulate GLP-1 release through soluble fiber and short-chain fatty acids produced during fermentation [9] - Avocados can increase GLP-1 levels due to their high fiber and monounsaturated fat content [9] - Olive oil, rich in unsaturated fats, has been shown to stimulate GLP-1 release more effectively than saturated fats [10] - Vegetables like Brussels sprouts, broccoli, and carrots are beneficial for regulating blood sugar and may influence GLP-1 levels [10]