中国农业大学发表最新Cell论文

Core Viewpoint - The research demonstrates that co-delivery of sensor and helper NLR immune receptors can overcome the "Restricted Taxonomic Functionality" (RTF) bottleneck, enabling the reconstruction of immune signaling pathways across distantly related plants [3][4]. Group 1: Research Findings - The study shows that the NLR genes from Solanaceae can function in non-asterid plants when co-delivered with their corresponding NRC-type helper NLR genes [11]. - By transferring the pepper Bs2 gene along with its homologous NRC-type helper NLR gene to rice, the rice was endowed with resistance to the bacterial blight caused by Xanthomonas oryzae pv. oryzicola (Xoc), which it originally lacked [11]. - The molecular mechanism involves the NRC helper protein forming a disease resistance signaling complex upon infection by Xoc, activating downstream immune responses [11]. Group 2: Implications for Agriculture - This breakthrough provides a feasible new strategy for the green control of crop diseases and offers important theoretical and practical demonstrations for future molecular design breeding across multiple species [4][8]. - The transgenic rice carrying the Bs2-NRC complex system showed no significant differences in baseline resistance or field adaptability compared to wild-type rice under non-pathogen-infected conditions, indicating ecological safety of the resistance system [11].