使用司美格鲁肽减肥，多久能看到疗效？

Core Viewpoint - The article discusses the effectiveness and timeline of the weight loss drug Semaglutide (Ozempic, Wegovy), highlighting that users can expect to see significant weight loss results within a few months of starting the treatment [2][4]. Summary by Sections Effectiveness of Semaglutide - Users of Semaglutide can expect to lose between 5% to 20% of their body weight within a year, depending on their initial weight [4]. - A study published in 2022 indicated that overweight or obese individuals lost an average of 5.9% of their weight after three months and 10.9% after six months of using Semaglutide [4]. Timeline of Effects - Initial absorption of Semaglutide occurs within 1-2 hours after subcutaneous injection [10]. - Peak concentration in the bloodstream is reached within 24-48 hours, where the drug actively binds to GLP-1 receptors [11]. - Noticeable effects, such as reduced appetite and improved blood sugar regulation, may begin within 1-2 weeks [12]. - Steady-state levels of the drug are achieved after 4-5 weeks, leading to more pronounced appetite suppression and accelerated weight loss [13]. Factors Influencing Effectiveness - Metabolism: Conditions like fatty liver, diabetes, and high blood sugar can complicate weight loss efforts and may delay the initial effects of Semaglutide [14]. - Age: Metabolism slows with age, potentially affecting the drug's efficacy, especially in individuals over 60 [15]. - Gender: Research suggests that women may experience better weight loss results with Semaglutide compared to men, possibly due to differences in body fat composition and insulin resistance [17]. - Concurrent Medications: Certain medications, such as chemotherapy drugs and steroids, can lead to weight gain, potentially diminishing the effectiveness of Semaglutide [18]. - Treatment Plan and Dosage: Higher doses of Semaglutide may lead to more noticeable effects and side effects, but the optimal dosage should be determined in consultation with a healthcare provider [19]. - Genetics: Individual genetic factors can influence the response to Semaglutide, leading to variability in effectiveness among users [20]. - Lifestyle Factors: Combining Semaglutide with lifestyle changes, such as exercise and a balanced diet, enhances weight loss outcomes [21].