Nature重磅发现：癌细胞从神经元中“窃取”线粒体，以增强自身能量，促进癌症转移

Core Viewpoint - The research highlights a novel biological signaling axis between nerves and cancer cells, revealing that cancer cells can hijack mitochondria from neurons to enhance their metastatic capabilities, thus providing new therapeutic targets for cancer treatment [4][5][6]. Group 1: Research Findings - The study published in Nature identifies that cancer cells utilize tubular structures to steal mitochondria from neurons, which helps them withstand stress during metastasis [4][5]. - The research team observed a universal phenomenon of mitochondrial transfer between neurons and cancer cells, confirming that cancer cells with stolen mitochondria generate more energy [11][12]. - Experiments showed that cancer cells that had acquired mitochondria from neurons had a significantly higher survival rate when subjected to stress conditions, indicating the importance of mitochondrial transfer in cancer metastasis [12]. Group 2: Implications for Cancer Treatment - The findings suggest a need for further investigation into the mechanisms of nerve-cancer cell mitochondrial transfer and the development of targeted therapies to prevent cancer metastasis [15]. - The research provides a compelling metabolic explanation for the observed dependency of cancer cells on the nervous system, which could apply to a broader range of cancers [15].