海南大学发表最新Nature论文

Core Viewpoint - The article discusses a groundbreaking study that presents a mouse brain stereotaxic topographic atlas with isotropic 1 μm resolution, which is expected to enhance multi-omics research at the single-cell level in neuroscience [3][6][8]. Group 1 - The research team, including academicians from Hainan University, Huazhong University of Science and Technology, and UCLA, published their findings in the journal Nature, detailing a 3D brain atlas for mice [3]. - The atlas, named STAM, provides a comprehensive dataset of 916 brain structures and allows for the generation of high-resolution images at any angle [6][8]. - The study utilizes continuous micro-optical sectioning imaging technology to create a dataset based on Nissl staining, achieving isotropic 1 μm resolution [6]. Group 2 - The STAM atlas is designed to support large-scale brain mapping projects by providing data analysis and visualization capabilities [8]. - It includes an informatics platform for visualizing and sharing atlas images, facilitating tasks such as brain slice registration and neuron circuit mapping [6]. - The atlas is compatible with widely used stereotaxic atlases, enabling cross-atlas navigation in both 2D and 3D spaces [6].