华人学者本周发表6篇Cell论文：RNA编辑器、植物细胞图谱、修饰腺苷的解毒机制、植物免疫、通用型CAR-T细胞、生物凝聚体

Core Insights - The article highlights nine research papers published in the prestigious journal Cell, with six authored by Chinese scholars, covering various advancements in molecular biology and plant science [3]. Group 1: RNA Editing and Gene Regulation - A study from Yale University transformed IscB and Cas9 into RNA-guided RNA editors, demonstrating potential applications in variable splicing interference and RNA base editing, with performance surpassing Cas13 and enhanced safety [5][7]. - The research on modified adenosines from Tohoku University revealed a detoxification mechanism involving adenosine kinase and ADAL, linking modified RNA metabolism to human diseases [14][17]. Group 2: Plant Science and Immunity - A unified cell atlas of vascular plants was created by researchers from the Chinese Academy of Sciences, identifying foundational genes and facilitating gene discovery, thus providing a new paradigm for plant developmental biology [9][12]. - A study on systemin antagonists in tomatoes uncovered a molecular mechanism regulating the plant immune system, which could inform the design of disease-resistant crops [19][22]. Group 3: CAR-T Cell Therapy - Researchers from Peking University developed a novel allogeneic CAR-T cell therapy by targeting the SPPL3 gene, which enhances the therapy's safety and efficacy, potentially revolutionizing CAR-T treatments [24][27]. Group 4: Neuroscience and Synaptic Plasticity - A study from Southern University of Science and Technology explored the material properties of postsynaptic density condensates, revealing how Shank3 oligomerization affects synaptic plasticity and could relate to autism spectrum disorders [29][32].