第四届合成生物与绿色生物制造大会成功举办！(下篇)

Core Viewpoint - The article discusses the advancements and applications of artificial intelligence (AI) in the field of biomanufacturing, highlighting various case studies and innovations presented at the SynBioCon 2025 conference [1][44]. Group 1: AI Empowerment in Biomanufacturing - The conference featured a series of activities promoting typical application cases of AI in biomanufacturing, including forums on AI-driven innovations [1][3]. - Shanghai Zhiyu Biotechnology introduced the "ZCloud Biocomputing Platform" and "ZBot Experimental Verification Platform," achieving the production of vanillin through enzyme methods at a scale of hundreds of tons [6]. - Baidu Biotechnology has emerged as a global leader in foundational models for life sciences, showcasing their xTrimoDNA and xTrimoProtein models and applications [7]. Group 2: Innovative Technologies and Applications - Dibil Biotechnology developed an intelligent dynamic and optimization system for microbial culture, enabling real-time prediction of intracellular metabolic flux [10]. - The roundtable discussion emphasized the importance of technology empowerment, scenario innovation, and ecological collaboration to drive high-quality industrial development [13]. - A high-throughput protein engineering platform was established, leading to the discovery of a new gene editing tool with a 40% efficiency increase and the identification of two new industrial enzymes with over ten times the catalytic activity of competitors [16]. Group 3: Future Food and Agriculture - The conference included discussions on the rapid growth of the global functional sugar market and the challenges in obtaining new functional sugars due to unclear biosynthesis pathways [28]. - The research center of Yili Group focused on developing a self-controlled probiotic R&D technology system tailored to the gut microbiome characteristics of the Chinese population [30]. - The report from Henglu Biotechnology highlighted the development of human milk oligosaccharides and their potential applications, with a focus on safety assessments for production strains [32]. Group 4: Industry Trends and Innovations - The article mentions the establishment of China's first enzymatic production line for vitamin A palmitate by Xinhai Biotechnology, which has entered into strategic cooperation for product development [33]. - The report from Zhejiang University discussed the development and application of biotechnology in fine chemical production [34]. - The potential of microalgae as a sustainable food source was emphasized, showcasing advancements in microalgae protein cultivation and its nutritional benefits [43].