盘点使用礼来替尔泊肽瘦下来的名人：怎么他们都瘦了这么多？

Core Viewpoint - The article discusses the effectiveness of Tirzepatide, a dual agonist of GIP and GLP-1 receptors, in weight loss, highlighting its clinical trial results and personal success stories from various individuals who have used the drug for weight management [6][8][9]. Group 1: Clinical Research Findings - Tirzepatide has shown significant weight loss results comparable to bariatric surgery in the SURMOUNT-1 study, where participants lost an average of 16.1 kg, 22.2 kg, and 23.6 kg in different dosage groups over 72 weeks, compared to a mere 2.4 kg in the placebo group [6]. - The drug operates by reducing food intake and increasing energy expenditure, while also delaying gastric emptying and suppressing appetite [6]. Group 2: Personal Success Stories - Dan Yongping reported a weight loss of 15 pounds (approximately 13.6 kg) after using Tirzepatide for two and a half months, noting improvements in his blood lipid levels without significant side effects [8]. - Whoopi Goldberg shared her experience of losing a substantial amount of weight, stating that she felt the drug was beneficial for those needing assistance with weight management [9][11]. - Lauren Manzo mentioned a weight loss of 30 pounds (approximately 27.2 kg) since starting Tirzepatide, expressing that it has been more effective than other weight loss methods, including surgery [12][13]. - Charles Barkley revealed a weight loss of 65 pounds (approximately 58.9 kg) while using Tirzepatide, emphasizing the drug's effectiveness in his weight loss journey [14][16].