南方科技大学发表最新Nature论文

Core Viewpoint - The research published in Nature demonstrates that amino acids possess a novel and widespread colloidal property, stabilizing proteins and colloidal dispersions through weak interactions [4][7]. Group 1: Amino Acids and Their Properties - Amino acids have a long history of use as stabilizers in biological media and are crucial components in biomedical formulations [3]. - The study reveals that amino acids can adsorb onto surfaces, providing stability to both proteins and colloidal dispersions, thus establishing a new theoretical model for predicting their effects [4][7]. - The research indicates that amino acids play a significant role in stabilizing protein folding states and may also act as solubilizers for proteins [6][7]. Group 2: Mechanisms and Applications - Various hypotheses have been proposed regarding the mechanisms by which amino acids exert their stabilizing effects, including their influence on water structure and hydrogen bonding [6]. - The study highlights that amino acids can enhance the bioavailability of insulin in the bloodstream, with the addition of 1M proline doubling its bioavailability [9]. - The findings provide a theoretical foundation and design tools for applications in drug formulation, protein stabilizers, and nanomaterials [4][9].