Core Insights - The global nucleic acid drug sector is entering a phase of accelerated commercialization, with BaiO SaiTu taking a significant step by signing an antibody option evaluation agreement with Merck to develop lipid nanoparticle delivery solutions for nucleic acid drugs [1] - BaiO SaiTu's dual business model, focusing on humanized animal models and a comprehensive human antibody library, addresses key challenges in drug development and aligns with industry demands for cost reduction and efficiency [2][3] Business Model and Innovation - BaiO SaiTu has developed over 4,390 gene-edited animal models, including more than 1,100 humanized models, leading to a revenue of 274 million yuan in the first half of 2025, a 56.1% year-on-year increase, with a gross margin of 79% [4] - The "Thousand Mice, Ten Thousand Antibodies" initiative aims to create a library of over one million human antibody sequences targeting more than 1,000 potential druggable targets, revolutionizing the traditional antibody selection process [4][5] Market Position and Global Expansion - BaiO SaiTu has established deep partnerships with the top ten global pharmaceutical companies, signing approximately 280 agreements for antibody molecule licensing, transfer, or co-development, covering major pharmaceutical markets worldwide [6][7] - The company has set up R&D and operational centers in key locations such as Boston, San Francisco, and Heidelberg to enhance local service capabilities and respond to market demands [7] Financial Performance - In the first half of 2025, BaiO SaiTu reported revenues of 621 million yuan, a 51.5% increase year-on-year, with overseas business accounting for approximately 70% of total revenue [8]
百奥赛图牵手默克:“双轮技术”模式竞逐全球核酸递送赛道