速递 | 女生滥用司美格鲁肽现酮症？盲目用药不可取

Core Viewpoint - The article highlights the misuse of GLP-1 medications, particularly semaglutide, leading to adverse effects among users who self-medicate without professional guidance [2][4]. Group 1: Misuse of GLP-1 Medications - Several individuals have reported side effects such as vomiting, nausea, and dizziness after misusing semaglutide for weight loss without medical supervision [2]. - A case is presented of a woman who, despite being underweight at 50 kg and 175 cm tall, self-administered semaglutide, resulting in severe symptoms including ketoacidosis [4]. Group 2: GLP-1 Drug Mechanism - GLP-1 (glucagon-like peptide-1) is a hormone produced by intestinal L cells, classified as an incretin, which enhances insulin secretion and suppresses glucagon release in a glucose-dependent manner [13]. - GLP-1 receptor agonists are designed to delay gastric emptying and reduce appetite, thereby aiding in blood sugar control and weight loss [13].