年轻人间断性高脂饮食，竟危害超乎想象！

Core Insights - The article emphasizes the increasing prevalence of dyslipidemia among adults in China, with a reported rate of 35.6% in individuals aged 18 and above as of 2018, highlighting the need for early intervention in blood lipid management [6][8]. Group 1: Health Risks and Findings - Dyslipidemia often presents no early symptoms, yet it can lead to significant vascular damage over time, increasing the risk of atherosclerotic cardiovascular diseases [6]. - Recent research suggests that the prevention of atherosclerosis should begin earlier in life, particularly focusing on the dietary habits of children and adolescents [6][9]. - A study conducted by Cambridge University found that young mice exposed to intermittent high-fat diets exhibited a significantly higher risk of atherosclerosis compared to those that were only exposed in later life [8][9]. Group 2: Research Implications - The findings indicate a strong correlation between elevated cholesterol levels in early life and the severity of atherosclerotic plaques in middle age [9]. - The research identified that early cholesterol elevation alters the gene expression of macrophages, which are crucial for clearing damaged cells and cholesterol, thereby weakening their protective function [9]. - Intermittent spikes in cholesterol levels, often due to dietary fluctuations, may pose greater risks than sustained high cholesterol, as seen in patients who irregularly take statins [9][11]. Group 3: Additional Studies - A concurrent study from Paris University also confirmed that intermittent high-fat diets accelerate atherosclerosis more than continuous high-fat diets, indicating a need for consistent dietary management [11].