盲人复明！马斯克Neuralink联创实现人工视觉里程碑

Core Viewpoint - The article highlights a groundbreaking advancement in artificial vision technology, specifically the PRIMA retinal implant, which has successfully restored functional central vision in patients suffering from age-related macular degeneration (AMD) [2][10][24]. Group 1: Technology Overview - The PRIMA system is a world-first artificial vision research project that utilizes a retinal implant to restore vision by acting as a substitute for light-sensitive cells [6][25]. - The device is a small photovoltaic retinal implant (2mm x 2mm x 30μm) that works wirelessly, powered by light captured through special glasses equipped with a camera [27]. - The system has shown promising results, with 84% of participants recovering functional central vision and 80% achieving a significant improvement in visual acuity [30]. Group 2: Patient Experience - Sheila Irvine, a 70-year-old participant, regained her vision after 15 years of blindness due to AMD, fulfilling her lifelong desire to read again [5][11]. - Prior to the experiment, Sheila described her vision as severely impaired, likening her eyes to "two black discs" [11]. - After the surgery and rehabilitation, she was able to recognize small text, demonstrating the potential of the PRIMA system to significantly enhance quality of life for patients [15][30]. Group 3: Clinical Trials and Results - The clinical trial involved 38 patients across 17 clinical sites in five countries, with evaluations conducted at 6 and 12 months post-implantation [29]. - The results indicated an average improvement of 25.5 letters (approximately 5 lines) in visual acuity for participants [30]. - While some patients experienced temporary adverse reactions, 95% of these symptoms resolved within two months, and there was no significant decline in peripheral vision [32]. Group 4: Future Prospects - The PRIMA system is currently undergoing regulatory approval processes in Europe and the U.S., with plans for a commercial launch in the near future [35]. - Researchers are also developing next-generation implants and glasses to enhance visual performance, aiming for smaller pixels and color vision capabilities [38]. - The project is seen as a significant step towards making "artificial vision" a reality, akin to the advancements made with cochlear implants for hearing [49].