夜间灯光危害大！《柳叶刀》子刊8万人研究：睡觉开灯增加67%糖尿病风险

Core Viewpoint - The article highlights a significant correlation between nighttime light exposure and the risk of developing type 2 diabetes, emphasizing the need for awareness and lifestyle adjustments to mitigate this risk [4][5][7]. Group 1: Nighttime Light Exposure and Diabetes Risk - A recent study involving 847,90 participants over 7.9 years found a dose-response relationship between nighttime light intensity and diabetes incidence, with a 67% increased risk for those exposed to high-intensity artificial light compared to low exposure groups [5][7]. - The study reported an incidence rate of 2.98 new cases of type 2 diabetes per 1,000 person-years, with a total of 1,997 new cases identified during the follow-up period [5][7]. - The research indicates that exposure to bright light during nighttime hours (00:30-06:00) correlates positively with diabetes risk, while higher light exposure during the day (07:30-20:30) is associated with a lower risk [7][8]. Group 2: Circadian Rhythm Disruption - Disruption of circadian rhythms due to excessive nighttime light exposure is linked to an increased risk of metabolic disorders, including type 2 diabetes [9]. - Individuals with altered circadian rhythms, whether phase-advanced or phase-delayed, show a significantly higher risk of developing diabetes compared to those maintaining normal rhythms [9]. - The study suggests that light exposure interferes with melatonin secretion, which may affect insulin sensitivity and glucose metabolism [9][10]. Group 3: Genetic and Environmental Factors - Nighttime light exposure and genetic predisposition are both independent predictors of type 2 diabetes risk, with similar predictive values [10]. - The research emphasizes the importance of considering both environmental factors, such as nighttime light exposure, and genetic background when assessing individual diabetes risk [10]. Group 4: Recommendations for Lifestyle Adjustments - The article advocates for lifestyle changes to reduce nighttime light exposure as a preventive strategy against metabolic diseases [11]. - Suggested measures include establishing regular sleep patterns, minimizing electronic device usage before bed, and ensuring a dark sleep environment [11]. - The findings serve as a reminder of the health implications of urban light pollution and the need for individuals to take proactive steps in managing their exposure to artificial light at night [11].